2nd Hands-on Computational Enzyme Design

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About the course

Do you need to engineer your protein of interest? Do you wish to employ user-friendly one-stop-shop software tools for the design of mutations and libraries, but do not want to spend time on tedious installations? This interactive course will provide the essential theory and hands-on experience on a number of web-based tools suitable for mining new enzyme, engineering the activity, specificity, enantioselectivity, stability, and solubility of enzymes.

You will have the chance to learn and discuss with the developers of these tools the optimal way to set-up calculations and adequately interpret the results. Special time will be devoted to the proteins of interest of the individual participants. At the end of this 2-day course, you will be able to independently design different properties of proteins for your academic research or commercial applications.

Web-tools covered: EnzymeMiner, HotSpot Wizard, Solubis, SoluProt, Caver Web, CaverDock, LoopGrafter, FireProt, FireProtASR, FireProtDBand CalFitter. Our web tools integrate individual software, and altogether, you will get automated access to more than 50 computational methods and 15 databases.


The 2nd edition of the course will be organized online for the safety reasons.


Program, registration and more details are at the course website.